Mixtures of Self-Modelling Regressions

نویسندگان

  • Rhonda D Szczesniak
  • Kert Viele
  • Robin L Cooper
چکیده

A shape invariant model for functions f1,...,fn specifies that each individual function fi can be related to a common shape function g through the relation fi(x)=aig(cix + di) + bi. We consider a flexible mixture model that allows multiple shape functions g1,...,gK, where each fi is a shape invariant transformation of one of those gk. We derive an MCMC algorithm for fitting the model using Bayesian Adaptive Regression Splines (BARS), propose a strategy to improve its mixing properties and utilize existing model selection criteria in semiparametric mixtures to select the number of distinct shape functions. We discuss some of the computational difficulties that arise. The method is illustrated using synaptic transmission data, where the groups of functions may indicate different active zones in a synapse. 0 50 100 150 200 -0 .1 0 -0 .0 5 0. 00 0. 05 0. 10 0. 15 (a)

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Adaptive Mixtures of Regressions: Improving Predictive Inference when Population has Changed

The present work investigates the estimation of regression mixtures when population has changed between the training and the prediction stages. Two approaches are proposed: a parametric approach modelling the relationship between dependent variables of both populations, and a Bayesian approach in which the priors on the prediction population depend on the mixture regression parameters of the tr...

متن کامل

Fitting finite mixtures of generalized linear regressions in R

R package flexmix provides flexible modelling of finite mixtures of regression models using the EM algorithm. Several new features of the software such as fixed and nested varying effects for mixtures of generalized linear models and multinomial regression for a-priori probabilities given concomitant variables are introduced. The use of the software in addition to model selection is demonstrate...

متن کامل

Application of Electrochemistry to Determination of Transfer Gibbs Energies and Autoprotolysis Constants for Aqueous Mixtures of Dimethyl Sulfoxide

A practical potentiometric method was applied successfully to experimental electrochemical data in order to determine the autoprotolysis constants (pKap) of water + dimethyl sulfoxide mixtures containing 0-90 % of DMSO by volume at 25° C and 0.1 M ionic strength was maintained in each mixture by NaClO4 solution. The results indicated that water-DMSO mixtures are more basic media than pure water...

متن کامل

Bayesian Time Series: Models and Computations for the Analysis of Time Series in the Physical Sciences

This articles discusses developments in Bayesian time series modelling and analysis relevant in studies of time series in the physical and engineering sciences. With illustrations and references, we discuss: Bayesian inference and computation in various state-space models, with examples in analysing quasi-periodic series; isolation and modelling of various components of error in time series; de...

متن کامل

Identifying Regression Outliers and Mixtures Graphically

Regressions in practice can include outliers and other unknown subpopulation structure. For example, mixtures of regressions occur if there is an omitted categorical predictor like gender or location and different regressions occur within each category. The theory of regression graphics based on central subspaces can be used to construct graphical solutions to long-standing problems of this typ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014